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  • Title: [Primary pulmonary cryptococcosis with endobronchial lesion].
    Author: Mito K, Kawano H, Yamakami Y, Arita K, Uenishi Y, Nagaoka H, Nagai H, Nasu M.
    Journal: Nihon Kokyuki Gakkai Zasshi; 2000 Apr; 38(4):302-6. PubMed ID: 10879035.
    Abstract:
    A 19-year old man was admitted to our hospital with fever and productive cough. Chest X-ray films revealed multiple nodular shadows accompanied by a fusing tendency in the right middle field. A diagnosis of bacterial pneumonia was indicated, and the patient was treated with antibiotics. However, because this failed to resolve the nodular shadows, bronchofibroscopy was performed. Examination with a fiberoptic bronchoscope revealed an elevated lesion in the truncus intermedius. Histopathologic examination of a specimen obtained by transbronchial biopsy revealed cryptococcal organisms with the infiltration of monocytes. These findings yielded a diagnosis of pulmonary cryptococcosis with endobronchial lesion. After 6 months of treatment with fluconazole, the multiple nodular shadows disappeared. Comparison of bronchoscopic findings before and after fluconazole treatment clearly demonstrated the efficacy of the therapy.
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