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  • Title: [Subcutaneous sarcoidosis of the extremities].
    Author: Iwanaga T, Fujise S, Takahashi N, Inuzuka S, Kishikawa R, Ikeda T, Shoji S, Nishima S.
    Journal: Nihon Kokyuki Gakkai Zasshi; 2000 Apr; 38(4):317-20. PubMed ID: 10879038.
    Abstract:
    A 65-year-old man was referred to our hospital due to abnormal chest roentgenograms showing bilateral hilar enlargement with diffuse micronodular opacities. He presented with uveitis and elevated serum ACE and tested negative for tuberculin response. Transbronchial lung biopsies as well as bronchoalveolar lavage were performed and yielded a diagnosis of sarcoidosis. Several months later, the patient showed multiple subcutaneous nodules around the knee joints and elbow joints with exacerbation of intrapulmonary lesions. A skin biopsy revealed multiple foci of typical non-caseating epithelioid cell granulomata. These pulmonary and subcutaneous lesions rapidly resolved in response to the systemic administration of corticosteroids. Subcutaneous sarcoidosis may be a subacute variant of sarcoidosis associated with systemic involvement.
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