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  • Title: [Antifibrinolytic and antimycotic properties of 2-thiontetrahydro-1,3,5-thiadiazine].
    Author: Kleking GR, Viurbakh G.
    Journal: Farmakol Toksikol; 1976; 39(4):432-6. PubMed ID: 1088410.
    Abstract:
    A series of tetrahydro-1,3,5-thiadiazine-2-thiones have been tested for their fungistatic and antifibrinolytic effects. The fungistatic activity depends upon the substitution of nitrogen in positions 3 and 5 of the ring system. But it is, however, only the derivatives that are able to split off the antifibrinolytically active w-amino acids by solvolysis which produces antifibrinolytic effect in vivo.
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