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  • Title: The 5S rRNA genes in Macaca fascicularis are organized in two large tandem repeats.
    Author: Jensen LR, Frederiksen S.
    Journal: Biochim Biophys Acta; 2000 Jul 24; 1492(2-3):537-42. PubMed ID: 10899597.
    Abstract:
    The 5S rRNA genes in Macaca fascicularis are organized in tandem repeats which are unusually large and complex. The tandem repeats consist of a 7.3 kb DNA fragment with two 5S rRNA genes linked to a 4.3 kb fragment with one gene. The total number of genes in the repeats is 50-100 per haploid genome. The 5S rDNA has an external promoter, the D box, in the same position relative to transcription start as the human gene but is transcribed less efficiently than a human 5S rRNA gene in a HeLa cell extract.
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