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  • Title: [Amenorrhoea after oral contraceptives].
    Author: Jürgensen O, Haslinger W, Eckert G, Dericks-Tan JS, Taubert HD.
    Journal: Dtsch Med Wochenschr; 1975 Feb 28; 100(9):406-9. PubMed ID: 1090431.
    Abstract:
    Eleven women with amenorrhoea after taking oral contraceptives were studied. A clomiphene stimulation test was performed in ten, with six also having an LH-RH stimulation test. In most of them there was no reaction or a severely impaired response to both clomiphene and LH-RH, but bleeding episodes could be provoked in most women by continuing clomiphene treatment, and some of these ovulated when HCG was added to the therapeutic scheme. A possible relationship between preexisting psychosomatic disorders and the genesis of postcontraceptive amenorrhoea is discussed. Amenorrhea was studied in 11 women aged 18-31 years who had been tre ated with combined oral contraceptives for 5 months-4 1/2 years. All were nulliparae, and had had normal cycles before treatment. In 10 patients a clomiphene stimulation test was performed, and 6 also had an LH-RH stimulation test. Impaired response was seen in 4 patients to the clomiphene, and continuation of clomiphene treatment combined with gestagens provoked hemorrhages. In 3 cases ovulation was induced when chorionic gonadotropin was added to the treatment. A possible relationship between preexisting psychosomatic disorders and the etiology of postcontraceptive amenorrhea is discussed.
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