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Title: IB-96212, a novel cytotoxic macrolide produced by a marine Micromonospora. II. Physico-chemical properties and structure determination. Author: Cañedo LM, Fernández-Puentes JL, Baz JP. Journal: J Antibiot (Tokyo); 2000 May; 53(5):479-83. PubMed ID: 10908111. Abstract: IB-96212, is a new member of spiroketal containing macrolide class of fermentation-derived natural products isolated from mycelial extracts of Micromonospora sp. The structure consists of a new aglycone which possesses a 26-membered macrolide ring system and of one deoxy sugar identified as L-rhodinose, this structure represents the first reported spiroketal macrolide natural product related to other macrolides, such as oligomycins, dunaimycins, citovaricin, rutamycin and ossamycin.[Abstract] [Full Text] [Related] [New Search]