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  • Title: Rapid progressive subacute sclerosing panencephalitis in a 2-year-old child with congenital athyreosis.
    Author: Lackmann GM, Hannen M, Madjlessi F, Lenard HG, Schroten H.
    Journal: Clin Infect Dis; 2000 Jul; 31(1):196-9. PubMed ID: 10913425.
    Abstract:
    We present the unique case of a 2-year-old girl with congenital athyreosis who acquired primary measles virus infection at the age of 18 months, coincidentally with an Epstein-Barr virus infection. First neurologic symptoms of subacute sclerosing panencephalitis appeared 5 months later, and the girl died within 6 months after a rapid progressive illness. Factors possibly predisposing to this extraordinary disease course-primary measles virus infection at an early age and lack of evidence for immunodeficiency-are discussed.
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