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  • Title: Dental caries and the microbial ecology of dental plaque: a review of recent advances.
    Author: Simmonds RS, Tompkins GR, George RJ.
    Journal: N Z Dent J; 2000 Jun; 96(424):44-9. PubMed ID: 10916359.
    Abstract:
    Our understanding of the microbial ecology of dental plaque has rapidly grown with recent developments in the techniques of molecular biology. In particular, knowledge of the mechanisms underlying the acquisition, establishment, pathogenicity, and evolution of the group of organisms responsible for dental caries--the mutans streptococci--has expanded to the point that we can now contemplate new opportunities for caries prevention. These advances reinforce developing concepts of dental plaque as an interdependent, interacting community of specialised organisms with an ability to rapidly adapt conferred by gene structures that facilitate the expeditious modular rearrangement of protein components.
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