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  • Title: Leukaemia in children. Part I: Orofacial complications and side-effects of treatment.
    Author: Ayers KM, Colquhoun AN.
    Journal: N Z Dent J; 2000 Jun; 96(424):60-5. PubMed ID: 10916364.
    Abstract:
    Significant orofacial complications of leukaemia in children include lymphadenopathy, spontaneous gingival bleeding, labial and lingual ecchymoses and mucosal petechiae, ulceration, gingival swelling, and infections. The dentist may be the first to notice signs of the illness. Treatment of leukaemia can result in serious orofacial problems which include oral mucositis and ulceration, infections, spontaneous gingival bleeding, neuropathy, xerostomia, and gingival hypertrophy. A prompt diagnosis leading to early intervention can decrease the morbidity and mortality of the disease and its treatment.
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