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  • Title: Ticlopidine-induced severe agranulocytosis after the placement of coronary artery stent--a case report.
    Author: Sari R, Sevinc A, Buyukberber S.
    Journal: Angiology; 2000 Jul; 51(7):591-3. PubMed ID: 10917583.
    Abstract:
    Ticlopidine is an oral antiplatelet agent frequently utilized in the treatment of cerebrovascular disease. It is rarely associated with severe bone marrow suppression. A case of an elderly woman is reported who developed febrile agranulocytosis two months after commencing ticlopidine but who had a favorable outcome after cessation of that drug and treatment with granulocyte colony-stimulating factor (G-CSF). All patients should have regular monitoring of their blood counts during therapy with ticlopidine.
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