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  • Title: Synthesis and antisecretory activity of 6-substituted 5-cyanomethylimidazo[2,1-b]thiazoles and 2,6-dimethyl-5-hydroxymethylimidazo[2,1-b][1,3,4]thiadiazole.
    Author: Andreani A, Leoni A, Locatelli A, Morigi R, Rambaldi M, Simon WA, Senn-Bilfinger J.
    Journal: Arzneimittelforschung; 2000 Jun; 50(6):550-3. PubMed ID: 10918949.
    Abstract:
    The synthesis of imidazo[2,1-b]thiazole and imidazo[2,1-b][1,3,4]thiadiazole derivatives, related to known antiulcer agents, is reported. 5-Cyanomethyl-6-methylimidazo[2,1-b]thiazole showed significant antisecretory activity in the isolated rabbit gastric glands assay.
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