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  • Title: [The effect of alpha-1 adrenergic blockade on the clinical course, immune status and blood plasma lipid spectrum in patients with ischemic heart disease].
    Author: Lizogub VG, Chumak AA, Savchenko AV, Pliskevich DA.
    Journal: Lik Sprava; 2000; (3-4):31-4. PubMed ID: 10921255.
    Abstract:
    Results are submitted of investigations designed to study effects of prazosine on the clinical course, immune and lipid spectrum of blood plasma in IHD patients with functional class I-II middle-aged and elderly-onset exertional angina. Efficiency of prazosine monotherapy was recordable in all FC I-II effort angina patients 30 to 50 years old, which fact was manifested by a decline in the number of angina attacks over the 24-hour period, number and duration of both pain and symptom-free myocardial ischemia, improvement in physical load tolerance. Also recordable in all patients was a positive effect of the drug on blood plasma lipid spectrum and certain immunological indices.
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