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  • Title: [Microscopic polyangiitis accompanying interstitial pneumonia with aluminum lung].
    Author: Seike M, Enomoto T, Henmi S, Uematsu K, Azuma A, Yoshimura A, Takasaki Y, Mochimaru H, Fukuda Y, Kudoh S.
    Journal: Nihon Kokyuki Gakkai Zasshi; 2000 May; 38(5):408-12. PubMed ID: 10921290.
    Abstract:
    A 67-year-old man who had worked as an aluminum grinder had been given a diagnosis of pneumoconiosis. Ten years later, he was admitted with fever, dyspnea on exertion, and numbness. Chest roentgenograms showed linear-reticular shadows in both lower lung fields. ELISA-based tests were positive for perinuclear anti-neutrophil cytoplasmic antibody (P-ANCA). Renal biopsy specimens disclosed crescentic glomerulonephritis and angiitis of small arteries. Our diagnosis was microscopic polyangiitis accompanying interstitial pneumonia with aluminum lung. The results of high-energy dispersion X-ray microanalysis indicated that the patient's lungs contained aluminum. His general condition improved with the administration of corticosteroid and immunosuppressive agents, and his chief symptoms disappeared.
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