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  • Title: [Anti-HIV chemoprophylaxis for blood-exposure accidents].
    Author: Bouvet E, Casalino E.
    Journal: Ann Med Interne (Paris); 2000 Jun; 151(4):283-90. PubMed ID: 10922956.
    Abstract:
    Chemoprophylaxis against HIV after accidental blood exposures represents a new indication for antiretroviral drugs. Efficacy has been suggested by the results of a case-control study in health care workers and the reduction of mother to infant transmission of HIV with zidovudine. The post-exposure treatment should be given as soon as possible, and in the latest at 48 hours. National guidelines recommend a triple therapy with or without protease inhibitor, adapted to the source patient. The evaluation of efficacy needs a standardized follow-up.
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