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  • Title: Rhegmatogenous retinal detachment in retinoblastoma patients undergoing chemoreduction and cryotherapy.
    Author: Anagnoste SR, Scott IU, Murray TG, Kramer D, Toledano S.
    Journal: Am J Ophthalmol; 2000 Jun; 129(6):817-9. PubMed ID: 10927003.
    Abstract:
    PURPOSE: To report the development of rhegmatogenous retinal detachment, with the retinal break adjacent to a cryotherapy scar, in three patients undergoing systemic chemotherapy for intraocular retinoblastoma. METHOD: Case series. RESULTS: Three patients with intraocular retinoblastoma were referred after poor response to systemic chemotherapy and local cryotherapy; three eyes of these three patients were noted to have rhegmatogenous retinal detachment and active retinoblastoma, with retinal breaks adjacent to cryotherapy scars. CONCLUSION: Rhegmatogenous retinal detachment may result from retinal necrosis associated with cryotherapy in the setting of intraocular retinoblastoma treated with systemic chemotherapy and local cryotherapy.
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