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  • Title: Metastatic ocular melanoma to the left ventricle inducing near-syncope attacks in an 84-year-old woman.
    Author: Rosario RT, DiMaio DJ, Lapham RL, Sweeney M, Smalling R, Barasch E.
    Journal: Chest; 2000 Aug; 118(2):551-3. PubMed ID: 10936157.
    Abstract:
    Cardiac tumors may represent mechanical causes for syncope by limiting left ventricular filling and/or by obstructing the left ventricular outflow tract. Malignant melanoma is known to metastasize to the myocardium or pericardium, but there are only a very limited number of reports describing endocardial involvement by the tumor. We describe herein an 84-year-old woman who presented with daily near-syncope episodes, 9 years after treatment for a choroidal melanoma. The echocardiography and the pathologic examination revealed a metastatic melanoma. This is the first reported case of an ocular melanoma metastasizing to the heart and presenting as a left ventricular intracavitary pedunculated mass.
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