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  • Title: Miconazole nitrate compared with chlordantoin in the treatment of vaginal candidiasis.
    Author: Morris DF, Sugrue DL.
    Journal: Br J Vener Dis; 1975 Apr; 51(2):123-4. PubMed ID: 1093633.
    Abstract:
    In a double-blind study of the treatment of vaginal candidiasis, miconazole nitrate gave a cure-rate of 88 per cent. (29 out of 33) compared with 58 per cent. (21 out of 36) using chlordantoin. Although approximately two-thirds of the patients who responded did so to a 10-day course of treatment, the different rates of cure with these preparations at this stage were not statistically significant. However, when a second course of treatment was given to those women who still had proven candidiasis, the overall cure-rate with miconazole was significantly greater than that with chlordantoin.
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