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  • Title: Comparative efficacy of ampicillin and trimethoprim-sulfamethoxazole in otitis media.
    Author: Cameron GG, Pomahac AC, Johnston MT.
    Journal: Can Med Assoc J; 1975 Jun 14; 112(13 Spec No):87-8. PubMed ID: 1093657.
    Abstract:
    Seventy-nine children with acute otitis media were the subjects in a study designed to compare the effectiveness of ampicillin and trimethoprim-sulfamethoxazole in this infection. They received either of these two agents according to a double-blind randomized procedure that also took the child's weight into account. No significant difference was found in the clinical outcome between the two treatment regimens. Undesirable side effects from TMP-SMX were notably few.
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