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  • Title: [Anterior pituitary regulation of testicular function in the elderly (author's transl)].
    Author: Becker H, Hofmann N, Kleissl HP, Kessel R, Lang E.
    Journal: Dtsch Med Wochenschr; 1975 May 30; 100(22):1225-8, 1233. PubMed ID: 1093834.
    Abstract:
    Pituitary gonadotrophin regulation was examined with the LH-RH test in 15 men (aged between 55 and 90 years), five of them aged between 71 and 90 years. Compared to normal mature males, the plasma testosterone in these subjects was reduced or was in the lower range of normal, while basal LH levels were increased in half the cases. However, basal FSH values were increased in three only. In most of these subjects with increased basal values of LH, the LH-RH stimulation caused a paradoxical temporary reduction in LH release which did not occur with FSH. This paradoxical response also did not occur when basal LH values were normal. Pituitary gonadotropin regulation was examined with the luteinizing hormone-releasing hormone (LH-RH) test in 15 men (aged 55-90 years). Compared to normal mature males, the plasma testosterone in these subjects was reduced or was in the lower range of normal, while basal LH levels were increased in half the cases. However, basal follicle stimulating hormone (FSH) values were increased in 3 only. In most of these subjects with increased basal values of LH, the LH-RH stimulation caused a paradoxical temporary reduction in LH release which did not occ ur with FSH. This paradoxical response also did not occur when basal LH values were normal.
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