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  • Title: Characterization of monoclonal antibodies against Hokkaido strain tick-borne encephalitis virus.
    Author: Komoro K, Hayasaka D, Mizutani T, Kariwa H, Takashima I.
    Journal: Microbiol Immunol; 2000; 44(6):533-6. PubMed ID: 10941938.
    Abstract:
    A tick-borne encephalitis (TBE) patient was found in Hokkaido in 1993, and TBE viruses were isolated from animals and ticks in our previous studies. To develop a diagnostic reagent to identify TBE viruses, monoclonal antibodies (Mabs) were produced against the TBE virus strain Hokkaido (Oshima 5-10). Seven Mabs were obtained which reacted with the envelope protein of the Oshima 5-10 strain. These Mabs were flavivirus genus-specific, TBE virus complex-specific or TBE virus type-specific. The Mabs are applicable for identification of TBE virus strains.
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