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  • Title: Vertebral hemangioma mimicking a metastatic bone lesion in well-differentiated thyroid carcinoma.
    Author: Laguna R, Silva F, Vazquez-Sellés J, Orduña E, Flores C.
    Journal: Clin Nucl Med; 2000 Aug; 25(8):611-3. PubMed ID: 10944016.
    Abstract:
    The authors report a case of abnormal accumulation of I-131 in a thoracic vertebra in a patient with a well-differentiated thyroid carcinoma. The presumptive diagnosis was metastatic bone disease. Further diagnostic work-up confirmed a benign bone lesion. Bone metastasis, when shown on I-131 whole-body scintigraphy, usually supports a change in the staging and therapeutic approach to a patient with thyroid carcinoma. The authors believe that, although an infrequent lesion, the differential diagnosis of abnormal accumulation of I-131 in the body of a vertebra in patients with well-differentiated thyroid carcinoma should raise the possibility of a benign hemangioma. Complete work-up of the suggested bone metastatic lesion should be performed before tumor restaging and I-131 therapy is recommended.
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