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  • Title: [Degradation of yeast mitochondria induced by anaerobiosis at the early stages of growth of the culture].
    Author: Luzikov VN, Raĭnia EI, Zubatov AS.
    Journal: Tsitologiia; 1975 Mar; 17(3):337-42. PubMed ID: 1094652.
    Abstract:
    Prolonged anaerobiosis of Saccharomyces cerevisiae cells result in degenerative changes in mitochondria which can be revealed when measuring the enzyme activities of the respiratory chain in isolated organellas and by electron microscope examination of the cells. The sensitivity of yeast mitochondria to anaerosiosis alters as the culture growth. Mitochondria are especially labile during the early expotential growth phase. Possible reasons for and mechanism of degradation of mitochondria in vivo are discussed.
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