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  • Title: Steroid sparing therapeutic approaches to polymyalgia rheumatica-giant cell arteritis. State of the art and perspectives.
    Author: Ferraccioli GF, Di Poi E, Damato R.
    Journal: Clin Exp Rheumatol; 2000; 18(4 Suppl 20):S58-60. PubMed ID: 10948766.
    Abstract:
    The therapeutic approach to polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) remains mainly based on corticosteroids. A few studies in PMR suggest a steroid-sparing effect with methotrexate in a subset of patients. No real alternative to steroids exists in GCA. Given the high chance of long-term treatment with corticosteroids in both diseases, randomized controlled trials with new immunosuppressive steroid-sparing drugs are eagerly awaited.
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