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  • Title: [Is nebulized ipratropium bromide effective in the treatment of exacerbations of chronic obstructive pulmonary disease?].
    Author: Musil J.
    Journal: Vnitr Lek; 2000 Jan; 46(1):45-8. PubMed ID: 10953664.
    Abstract:
    The author administrated to 20 patients hospital on account of exacerbation of chronic obstructive pulmonary disease nebulized ipratropium bromide 0.5 mg on admission. Nebulized was repeated, using the same dose after 30 mins. The PEF value increased significantly after the first and second nebulization. After the two nebulizations dyspnoea was alleviated. The value of the respiration rate was significantly lower after both nebulizations as compared with the value before treatment. PaO2 increase significantly as compared with the value before treatment. PaO2 and the pulse rate did not change. An undesirable effect was recorded in one patient. Ipratropium bromide administration in effective and safe.
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