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  • Title: Enzymic in vitro repair and chemical nature of DNA chain breaks induced by incorporated phosphorus-32P decay.
    Author: Fodor I, Matvienko NI, Zlotnikov KM, Tanyashin VI, Solonin AS, Bayev AA.
    Journal: Nucleic Acids Res; 1975 May; 2(5):635-46. PubMed ID: 1096080.
    Abstract:
    In vitro repair of single strand breaks in T4 and phage DNA caused by 32p decay was studied. Zone centrifugation procedure showed that polynucleotide kinase, ligase enzyme system failed to repair 32P-damages. It was found that damaged DNA contained gaps and could be repaired by DNA-polymerase I, polynucleotide ligase treatment.
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