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  • Title: Pyloric reflux gastritis: the offending agent.
    Author: Delaney JP, Broadie TA, Robbins PL.
    Journal: Surgery; 1975 Jun; 77(6):764-72. PubMed ID: 1096345.
    Abstract:
    Tubes of canine gastric corpus were constructed so that the mucosa was exposed chronically to jejunal contents, pancreatic juice, or bile. Biopsies of these mucosae obtained 4 to 24 months later were compared with each other and with the normal stomach for parietal cell numbers, mucus cell numbers, inflammation, glandular disorder, and surface-cell hyperplasia. All three preparations showed marked gastrititis, but whole jejunal contents caused more severe changes than did either pancreatic juice or bile, which were approximately equal.
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