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  • Title: Effect of melatonin on lenticular calcium and magnesium in rats exposed to ultraviolet radiation.
    Author: Bardak Y.
    Journal: Ophthalmologica; 2000; 214(5):350-3. PubMed ID: 10965250.
    Abstract:
    Six-week-old rats received 8 kJ/m(2) ultraviolet B (UVB) for 15 min. For the intervention in cataract development, intraperitoneal injection of melatonin (4 mg/kg daily for 1 week) following UVB exposure was performed. Lenticular calcium and magnesium levels were determined in UVB + melatonin, UVB and control groups. One week after exposure, significantly more cataractous changes were observed in the UVB group than the UVB + melatonin group. The mean lens calcium and magnesium levels for the UVB group were significantly higher than those for the control and the UVB + melatonin groups. There were no significant differences between the control and the UVB + melatonin groups for the mean lens calcium and magnesium levels.
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