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  • Title: Retroperitoneal endoscopic debridement for infected peripancreatic necrosis.
    Author: Seifert H, Wehrmann T, Schmitt T, Zeuzem S, Caspary WF.
    Journal: Lancet; 2000 Aug 19; 356(9230):653-5. PubMed ID: 10968442.
    Abstract:
    Standard management of infected peripancreatic necrosis consists of open surgical debridement and lavage--a traumatic intervention with substantial morbidity and mortality. As an alternative and novel approach with minimum invasiveness, we present fenestration of the gastric wall and debridement of infected necrosis by direct retroperitoneal endoscopy. In three patients, this strategy led to rapid clinical improvement and no serious complications. Transgastric endoscopic therapy may be a less traumatic alternative to surgery and should be further assessed in prospective studies.
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