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  • Title: Transformation of hepatitis B virus-related membranous glomerulonephritis to crescentic form.
    Author: Taskapan H, Oymak O, Dogukan A, Ozbakir O, Utas C.
    Journal: Clin Nephrol; 2000 Aug; 54(2):161-3. PubMed ID: 10968695.
    Abstract:
    We report a case of hepatitis B virus-(HBV) related membranous glomerulonephritis which progressed to crescentic transformation after withdrawal of immunosuppressive treatment. Immunosuppressive therapy probably enhanced HBV replication, and its withdrawal led to a return of immune competence resulting in progression of the glomerulonephritis. Prior screening of all patients for hepatitis B surface antigen, before using immunosuppressive therapy may prevent this complication. The usage of immunosuppressive therapy as a first-line choice in HBV-related glomerulonephritis may result in harmful complications.
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