These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The treatment of tetanus with intrathecal baclofen.
    Author: Boots RJ, Lipman J, O'Callaghan J, Scott P, Fraser J.
    Journal: Anaesth Intensive Care; 2000 Aug; 28(4):438-42. PubMed ID: 10969374.
    Abstract:
    The treatment of severe tetanus generally requires prolonged mechanical ventilation. We describe two cases managed with continuous intrathecal infusion of baclofen via a subcutaneous tunnelled spinal catheter and an abdominal injection port. Baclofen, by diminishing spasms and spasticity, allowed reduced sedation and paralysis requirements. This potentially decreases the time and resources required for intensive care management. Complications include sedation, hypotension and CSF infection. After appropriate dose adjustment, baclofen improves the management of severe tetanus.
    [Abstract] [Full Text] [Related] [New Search]