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Title: The total synthesis of piclavines A1-4 and their biological evaluation. Author: Takahata H, Okamoto N. Journal: Bioorg Med Chem Lett; 2000 Aug 21; 10(16):1799-801. PubMed ID: 10969971. Abstract: The total synthesis of piclavines A1, A2, A3, and A4 has been achieved starting from compound 10 with enantiomeric enhancement. Their biological activities (antibacterial, antimicrobacterial, and antiviral activities and inhibition of cell growth) were evaluated.[Abstract] [Full Text] [Related] [New Search]