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  • Title: Human thymus-derived rosette-forming cells and immunologic diseases.
    Author: Wybran J, Fudenberg HH.
    Journal: Birth Defects Orig Artic Ser; 1975; 11(1):7-9. PubMed ID: 1096998.
    Abstract:
    This paper describes some studies done on the human lymphocytes that bind to normal sheep red blood cells in a rosette formation. On the basis of human fetal studies and investigations of markers for B cells, it is demonstrated that rosette-forming cells are valid markers for T cells. These cells were looked at in various immunologic diseases. A modification of the basic technic, one that detects subpopulations of lymphocytes, was mainly used. Results correlate closely with the cellular immune status of the patient.
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