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  • Title: Synthesis of 7alpha-hydroxy derivatives of regulatory oxysterols.
    Author: Li D, Spencer TA.
    Journal: Steroids; 2000 Sep; 65(9):529-35. PubMed ID: 10978732.
    Abstract:
    7alpha-Hydroxy derivatives of oxysterols are of considerable interest because of their possible involvement in regulation of cholesterol metabolism. This paper describes stereoselective syntheses and complete characterization of the 7alpha-hydroxy derivatives of four key oxysterols: 25-hydroxycholesterol, 27-hydroxycholesterol, 24(S)-hydroxycholesterol, and 24(S), 25-epoxycholesterol.
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