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  • Title: Reversible pulmonary hypertension in POEMS syndrome--another etiology of triggered pulmonary vasculopathy?
    Author: Paciocco G, Bossone E, Erba H, Rubenfire M.
    Journal: Can J Cardiol; 2000 Aug; 16(8):1007-12. PubMed ID: 10978936.
    Abstract:
    Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes (POEMS) syndrome, a plasma cell dyscrasia associated with pulmonary hypertension, has been treated in the past with anticytokine strategies with a poor outcome. A patient is described who had POEMS syndrome with precapillary pulmonary hypertension and Raynaud's phenomenon, and who responded well to a short course of corticosteroids and long term nifedipine. POEMS syndrome, like anorexigens, cocaine, portal hypertension and human immunodeficiency virus infection, may be another trigger for the pulmonary vascular occlusive process found in primary pulmonary hypertension.
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