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  • Title: Toll signaling: the enigma variations.
    Author: Wasserman SA.
    Journal: Curr Opin Genet Dev; 2000 Oct; 10(5):497-502. PubMed ID: 10980426.
    Abstract:
    Experiments reported in the past year have revealed considerable diversity in Toll-mediated pathways for signal transduction in development and innate immunity. Rather than function as a well conserved signaling cassette, Toll receptors and associated factors have apparently evolved as a diverse set of configurations to defend against microbial infection in species ranging from plants to humans.
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