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Title: A fraction isolated from Ehrlich ascites carcinoma as an antitumor and differentiating agent against human leukemic cell ML-2. Author: Sur P, Nandi N, Ghosh P, Ghosh NC. Journal: Neoplasma; 2000; 47(2):114-7. PubMed ID: 10985477. Abstract: Lipopolysaccharide fraction isolated from Ehrlich ascites carcinoma (E-LPS) was investigated as an antitumor agent against human leukemia cell ML-2. Marked cell growth inhibition was observed with ML-2 cell accompanied by inhibition of DNA synthesis and perturbation of cell cycle. Induction of differentiation in treated ML-2 cells was observed as indicated by morphological maturation, NBT reducing activity and indirect immunofluorescence.[Abstract] [Full Text] [Related] [New Search]