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  • Title: Althesin and thiopentone: a clinical comparison.
    Author: Obdrizalek J.
    Journal: Can Anaesth Soc J; 1975 Sep; 22(5):601-6. PubMed ID: 1098751.
    Abstract:
    Althesin was compared with thiopentone in a double blind study of 200 patients undergoing gynaecological operations. Althesin in a dose of 0.05 ml/kg was found to be an excellent induction agent, virtually devoid of undesirable side effects; however, when used as the principal anaesthetic (supplemented only by 66 per cent nitrous oxide in oxygen), the incidence of disturbing movements was high. Recovery time from Althesin was one-third of that after thiopentone. The patients recovering from Althesin were remarkably clearheaded with a low incidence of "hangover".
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