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  • Title: Doxycycline in the treatment of upper and lower respiratory tract infections. A field trial.
    Author: Titscher R.
    Journal: Chemotherapy; 1975; 21 Suppl 1():109-15. PubMed ID: 1098871.
    Abstract:
    As part of the Pan-European multi-centre trial of doxycycline in the treatment of respiratory tract infections during the winter of 1973/1974, a field trial was carried out in Austria. 95 physicians provided 540 case reports for evaluation. Very good or good results were obtained in 93.9% of patients and the rate of improvement as indicated by fall in temperature, reduction in cough, sputum and pain, and easing of inflammatory symptoms was rapid; 77.8% of patients showed complete remission of acute symptoms after 3 days of treatment. Only 5.6% of patients suffered from side-effects which were mostly mild. Comparison with a previous field trial in Austria in 1968/1969 showed that doxycycline has retained its efficacy over the years.
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