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  • Title: Severe pancytopenia after leflunomide in rheumatoid arthritis.
    Author: Auer J, Hinterreiter M, Allinger S, Kirchgatterer A, Knoflach P.
    Journal: Acta Med Austriaca; 2000; 27(4):131-2. PubMed ID: 10989684.
    Abstract:
    Leflunomide is a novel drug recently introduced for treatment of rheumatoid arthritis as a DMARD (disease-modifying antirheumatic drug). So far, leflunomide has not been associated with severe bone marrow toxicity and pancytopenia. We report of a 62-year-old woman with a 14-year history of rheumatoid arthritis with bone marrow toxicity and reversible pancytopenia developing after treatment with leflunomide.
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