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  • Title: [Relation between retinal pigment epithelial detachment and dye leakage in central serous retinopathy].
    Author: Constantinides G.
    Journal: J Fr Ophtalmol; 2000 Sep; 23(7):649-54. PubMed ID: 10992059.
    Abstract:
    PURPOSE: The purpose of this report is to provide supportive evidence favoring the hypothesis of choroidal hyperpermeability in central serous chorioretinopathy. PATIENTS AND METHODS: Seven consecutive patients (eight eyes) with a history of central serous chorioretinopathy were explored. Fluorescein angiography and a monochromatic frame at 640 mm was performed for all eyes. All showed dye leakage located at the rim of a retinal pigment epithelial detachment. RESULTS: Retinal pigment epithelial detachment was extrafoveal in all 8 eyes. Dye leakage was located at the nasal rim in 4 eyes, the superior rim in 2 eyes, the temporal rim in 1 and the anterior rim in the last eye. CONCLUSION: Dye leakage at the rim of pigment epithelial detachment in central serous chorioretinopathy is a strong argument for the hypothesis of a choroidal hyperpermeability. The hyperpressure crushes the overlying retinal pigment epithelium and in some areas provokes focal detachment and dye leakage at the junction of the detached and attached pigment epithelium.
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