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  • Title: Relationship among skin tests, bronchial challenge and serology in house dust and Candida albicans allergic asthma.
    Author: Kurimoto Y.
    Journal: Ann Allergy; 1975 Sep; 35(3):131-41. PubMed ID: 1099944.
    Abstract:
    One hundred and ninety-six asthmatic patients were examined by inhalation challenge using house dust and candida albicans; an early, dual or late bronchial response was induced where IgE, C3 and C4 were elevated. In some of late responses by candida inhalation there was a decrease or almost no increase in IgE and a fall in C3 and C4. There was a considerable correlation between skin tests and bronchial responses. An induced bronchial response, early, dual or late, was identified as Type I, While candida-induced late bronchial responses were Type I and Type III. There is some question whether Type I plus Type III mechanism may be involved in the dual bronchial response provoked with candida.
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