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Title: 7-Methoxybenzofuran-4-carboxamides as PDE 4 inhibitors: a potential treatment for asthma. Author: Buckley G, Cooper N, Dyke HJ, Galleway F, Gowers L, Gregory JC, Hannah DR, Haughan AF, Hellewell PG, Kendall HJ, Lowe C, Maxey R, Montana JG, Naylor R, Picken CL, Runcie KA, Sabin V, Tuladhar BR, Warneck JB. Journal: Bioorg Med Chem Lett; 2000 Sep 18; 10(18):2137-40. PubMed ID: 10999488. Abstract: The synthesis and pharmacological profile of a novel series of 7-methoxybenzofuran-4-carboxamides is described. Some of these compounds were found to be potent inhibitors of phosphodiesterase type 4 (PDE4).[Abstract] [Full Text] [Related] [New Search]