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  • Title: Preparation and antidiabetic activity of new substituted 3,5-diarylpyrazolesulfonylurea derivatives. II: Structure-activity relationship.
    Author: Soliman R, Faid-Allah HM, el-Sadany SK.
    Journal: J Pharm Sci; 1987 Aug; 76(8):626-32. PubMed ID: 11002821.
    Abstract:
    Four series of substituted p-(3,5-diaryl-2-pyrazoline-1) benzenesulfonylurea and thiourea derivatives, along with their corresponding substituted p-(3,5-diarylpyrazole-1) benzenesulfonylurea and thiourea derivatives, were prepared for evaluation as hypoglycemic agents. Preliminary biological testing revealed that the new compounds possess potent hypoglycemic activity.
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