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  • Title: [Use of intrapleural urokinase in children].
    Author: Tapia Ceballos L, Picazo Angelín B, Bonillo Perales A, Romero Sánchez J, Díaz Cabrera R, Romero González J.
    Journal: An Esp Pediatr; 2000 Mar; 52(3):281-4. PubMed ID: 11003910.
    Abstract:
    OBJECTIVE: To present the use of intrapleural urokinase as an alternative to surgical management of complicated pleural effusions in children. To add new cases to the literature and set bases for the development of a standardized protocol. METHOD: Presentation of three cases in children under three years of age treated with intrapleural urokinase. RESULTS: Resolution of the effusions with lack of adverse effects. CONCLUSION: Treatment of pleural effusions when loculations develop. This invasive approach might be avoided in some cases by instillation of a fibrinolytic agent such as urokinase into the pleural space, this being an efficient and safe procedure.
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