These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Intensified physiotherapy improves fitness to fly in cystic fibrosis patients.
    Author: Kamin WE, Fleck B, Rose D.
    Journal: Eur J Med Res; 2000 Sep 18; 5(9):402-4. PubMed ID: 11003975.
    Abstract:
    OBJECTIVES: The life expectancy for patients with cystic fibrosis has risen constantly within the last 10 years to an average age over 20 years in western countries. However, most of these patients are partially respiratory insufficient. Frequently their physicians must decide whether it is acceptable to expose them to reduced air pressure on board of an aeroplane during long distance flights or how their fitness to fly can be improved prior to their annual vacation. We investigated the effect of intensified daily physiotherapy -carried out during a four weeks stay on Gran Canaria, Spain- on lung-function parameters, oxygen saturation and saliva neopterin as marker for ongoing inflammation in the respiratory tract. METHODS: 10 out of 12 patients (age 19 34 years, mean 28.6 years) were investigated two weeks prior and two weeks after their trip to the Canaries, Spain. Lung function on ground level and during flights to and from the island, oxygen saturation and saliva-flow adjusted neopterin in saliva were measured. RESULTS: Over the entire group vital capacity (VC) improved significantly from 2.89 l (range 1.37 3.95) to 3.36 l (range 1.23 5.24). Intrathoracic gas volume as a sign for pulmonary hyperinflation- declined slightly from 3.79 l (range 2.06 6.17) to 3.48 l (range 2. 18 5.85). The oxygen saturation increased from 89.5% (range 79 - 92%) during the flight to the Canaries to 94% (range 82 - 96%) during the return flight. Saliva neopterin dropped from 0.8 pmol/min. (range 0.2 6.8 pmol/min) to 0.6 ( range 0.1 2.6 pmol/min) pointing to diminished inflammation in the respiratory tract. CONCLUSION: Our results indicate that fitness to fly can be improved by intense physiotherapy as shown by improvement of vital capacity and oxygen saturation during flight. The influence of an additional climate change on the improvement of lung function in CF-patients needs further evaluation.
    [Abstract] [Full Text] [Related] [New Search]