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  • Title: Ribonuclease P: a ribonucleoprotein enzyme.
    Author: Kurz JC, Fierke CA.
    Journal: Curr Opin Chem Biol; 2000 Oct; 4(5):553-8. PubMed ID: 11006544.
    Abstract:
    The ribonucleoprotein ribonuclease P catalyzes the hydrolysis of a specific phosphodiester bond in precursor tRNA to form the mature 5' end of tRNA. Recent studies have shed light on the structures of RNase-P-RNA-P-protein and RNase-P-RNA-precursor-tRNA complexes, as well as on the positions of catalytic metal ions, emphasizing the importance of the structure to the catalytic function.
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