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Title: Nitrogenase: standing at the crossroads. Author: Rees DC, Howard JB. Journal: Curr Opin Chem Biol; 2000 Oct; 4(5):559-66. PubMed ID: 11006545. Abstract: Nitrogenase catalyzes the ATP-dependent reduction of dinitrogen to ammonia, which is central to the process of biological nitrogen fixation. Recent progress towards establishing the mechanism of action of this complex metalloenzyme reflects the contributions of a combination of structural, biochemical, spectroscopic, synthetic and theoretical approaches to a challenging problem with implications for a range of biochemical and chemical systems.[Abstract] [Full Text] [Related] [New Search]