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  • Title: [Primary bilateral adrenal lymphoma].
    Author: Cachat M, Fontana E, Delacrétaz F, Zadory J, Gomez F, Lamy O.
    Journal: Schweiz Med Wochenschr; 2000 Aug 08; 130(31-32):1120-4. PubMed ID: 11008305.
    Abstract:
    When abdominal imaging reveals the existence of unsuspected adrenal masses, a diagnostic strategy is necessary. We report the case of a woman presenting with pulmonary embolism, in whom abdominal ultrasound revealed voluminous masses in both adrenals without clinical or biological signs of hormone hypersecretion, but with mild primary adrenal failure. From a CT scan-directed needle biopsy of the right adrenal mass and subsequent staging we were able to diagnose a primary bilateral adrenal lymphoma, diffuse large B-cell type (REAL/WHO). On CHOP chemotherapy both adrenal masses decreased dramatically and the patient is in remission 18 months later. Primary adrenal lymphoma is a rare condition, since 65 cases have been reported to date. Histological diagnosis is nevertheless important, in view of the excellent response to specific therapy observed in some cases.
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