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  • Title: [Participation of phytohemagglutinin-transformed mouse lymphocytes in development of the "graft-versus-host" reaction].
    Author: Nesterenko VG, Koval'chuk LV.
    Journal: Biull Eksp Biol Med; 1976 Sep; 82(9):1096-8. PubMed ID: 11013.
    Abstract:
    Transformed lymphocytes obtained as a result of phytohemagglutinin-stimulation of the cells of the lymph nodes of the CBA mice were incapable of realizing the graft-versus-host reaction in administration to the sublethally irradiated (CBAXC57BL/6) F1 hybrids. In this case the graft-versus-host reaction is induced by small untransformed lymphocytes with the same concentration of surface antigens detected by the antilymphocytic serum as in the intact lymphocytes.
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