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  • Title: Neuroblastomatous recurrence of ganglioglioma. Case report.
    Author: David KM, de Sanctis S, Lewis PD, Noury AM, Edwards JM.
    Journal: J Neurosurg; 2000 Oct; 93(4):698-700. PubMed ID: 11014552.
    Abstract:
    This case is believed to be the first reported recurrent intracranial ganglioglioma with purely neuroblastomatous malignant transformation. A complete macroscopic resection of a right frontal lobe tumor in an 18-year-old woman revealed differentiated ganglioglioma. Seven years later a large, well-demarcated recurrent tumor was again macroscopically totally resected in the same patient. Histological analysis showed malignant transformation in only the neuronal component of the original tumor. A review of the literature on recurrent gangliogliomas and their malignant transformation is included.
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